NucleoSkin: India’s Most Advanced PDRN Skin Booster for Repair, Radiance & Rejuvenation
- Ankit Singla
- 13 minutes ago
- 3 min read

Skin boosters are one of the fastest-growing aesthetic treatments worldwide. But as the market becomes crowded with HA-based injectables, dermatologists are increasingly looking for next-generation, regenerative formulas that go beyond hydration alone.
Enter NucleoSkin — a breakthrough Italian skin booster powered by PDRN, Hyaluronic Acid, and Glutathione, designed for deep repair, brightening, anti-ageing, and skin regeneration.
In this blog, we explore why NucleoSkin is quickly becoming a favourite among dermatologists across India.
What Is NucleoSkin?
NucleoSkin is an injectable bio-regenerative skin booster formulated in Italy. It combines three clinically powerful ingredients:
PDRN 2% – for healing, repair, collagen stimulation
Hyaluronic Acid (10 mg/ml) – for hydration, elasticity and glow
Glutathione 2 mg/ml – for brightening & antioxidant protection
This potent trio makes NucleoSkin ideal for rejuvenating dull, ageing, pigmented, or stressed skin.
Why PDRN Is the Real Game-Changer

PDRN (PolyDeoxyRiboNucleotide) is a regenerative molecule derived from DNA fragments. It has been used in wound healing, tissue repair, and aesthetic medicine for over a decade.
Key Benefits of PDRN:
1. Stimulates collagen & elastin
PDRN activates fibroblasts — the cells responsible for collagen production — leading to firmer, younger-looking skin.
2. Repairs damaged skin
It accelerates tissue regeneration, making it ideal for:
Acne scars
Sun-damaged skin
Over-exfoliated skin
Post-procedure healing
3. Reduces inflammation
Helps calm sensitive, irritated, or rosacea-prone skin.
4. Improves cell turnover
Promotes younger skin by accelerating the natural renewal cycle.
5. Deep hydration support
Works synergistically with HA for plump, glowing skin.
In short: PDRN delivers regeneration that HA alone cannot.
Why NucleoSkin Is Different From Other Skin Boosters
Most skin boosters in India are only Hyaluronic Acid.NucleoSkin stands out because it is a regenerative + hydrating + brightening formula in one.
✓ Stronger repair than standard HA boosters
Because of PDRN’s tissue-regenerating effect.
✓ Better glow & pigmentation control
Because Glutathione supports antioxidant and brightening activity.
✓ Suitable for younger + mature patients
From dullness to fine lines, to post-acne concerns.
✓ Works on face, eyes, neck & hands
A true multi-area booster.
✓ Faster recovery after procedures
Ideal post-laser, post-peel or post-microneedling.
This makes NucleoSkin one of the most versatile boosters in your portfolio.
What Skin Concerns Does NucleoSkin Treat?

NucleoSkin is effective for:
Dull, tired-looking skin
Fine lines and early ageing
Acne-scarred or textured skin
Pigmentation & uneven tone
Dehydrated or rough skin
Crepey under-eye skin
Photoaging (sun damage)
Smokers’ skin
Post-inflammatory pigmentation
Dermatologists also use it as a pre-event glow treatment for weddings, shoots, and special occasions.
Treatment Areas for NucleoSkin
NucleoSkin can be used safely on:
Face
Under-eye region
Neck
Hands
Décolletage
Acne-scarred areas
Each area responds with improved elasticity, brightness, texture, and volume support.
How Is NucleoSkin Administered?
It is injected through:
Micro-injection techniques (nappage)
Cannula for deeper rejuvenation
Bio Aesthetic Points
Dermatologists choose technique based on concern and area.
Recommended Session Plan
Standard Protocol
3-4 sessions
3–4 weeks apart
Maintenance
Every 4–6 months
Timeline of Results
Immediately: Hydration & glow
2–3 weeks: Brighter complexion & smoother texture
4–6 weeks: Reduced fine lines, improved firmness
8–12 weeks: Regeneration, improved scarring, tighter skin
Results continue improving over several weeks because of PDRN’s ongoing repair activity.
NucleoSkin vs Other Popular Boosters
Feature | NucleoSkin | Pure HA Boosters | Polynucleotide-Only Boosters |
Hydration | ★★★★★ | ★★★★★ | ★★★★☆ |
Repair & Healing | ★★★★★ | ★★☆☆☆ | ★★★★★ |
Brightening | ★★★★☆ | ★★☆☆☆ | ★★★☆☆ |
Anti-ageing | ★★★★★ | ★★★☆☆ | ★★★★☆ |
Under-eye compatibility | Excellent | Good | Excellent |
Post-laser recovery | Excellent | Moderate | Excellent |
NucleoSkin offers a triple-benefit formula unmatched by most competitors.
Who Is the Ideal Candidate for NucleoSkin?
Perfect For:
Age 20+ with dullness or early ageing
Brides & grooms preparing for events
Patients wanting a natural glow
Acne-scarred patients
Smokers
Those not ready for fillers or lasers
Patients wanting under-eye rejuvenation
Not Ideal For:
Those expecting filler-like volume
Severe photoaging requiring lasers first
Why Dermatologists Prefer NucleoSkin

Predictable results
Multi-ingredient synergy (PDRN + HA + Glutathione)
Excellent patient satisfaction
High repeat rate
Works beautifully with lasers, microneedling & peels
Strong safety profile
NucleoSkin stands out as a high-margin, high-results booster in the clinic.
Cost of NucleoSkin Treatment in India
Pricing varies by concern and clinic, but patients can expect:
₹10,000 – ₹30,000 per session
Package (3 sessions): ₹30,000 – ₹70,000
Premium dermatologists may charge more based on expertise, technique and quantity of booster consumed.
Is NucleoSkin Worth It?
If you want:
Glowing skin
Improved texture
Reduced pigmentation
Firmer, younger-looking appearance
Better under-eye quality
Smoother lines
Stronger skin health
…then yes, NucleoSkin is one of the most effective regenerative boosters available in India today.
It delivers hydration (HA), regeneration (PDRN), and brightness (Glutathione) — all in one session.






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